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[[Image:2qor.jpg|left|200px]]


{{Structure
==Crystal structure of Plasmodium vivax guanylate kinase==
|PDB= 2qor |SIZE=350|CAPTION= <scene name='initialview01'>2qor</scene>, resolution 1.800&Aring;
<StructureSection load='2qor' size='340' side='right'caption='[[2qor]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=5GP:GUANOSINE-5&#39;-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>
<table><tr><td colspan='2'>[[2qor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QOR FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= Pv099895, PVX_099895 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5855 Plasmodium vivax])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071 GMPK]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qor OCA], [https://pdbe.org/2qor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qor RCSB], [https://www.ebi.ac.uk/pdbsum/2qor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qor ProSAT]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qor OCA], [http://www.ebi.ac.uk/pdbsum/2qor PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2qor RCSB]</span>
</table>
}}
== Function ==
[https://www.uniprot.org/uniprot/A5K709_PLAVS A5K709_PLAVS]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qo/2qor_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qor ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Plasmodium vivax guanylate kinase'''
==See Also==
 
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2QOR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QOR OCA].
[[Category: Large Structures]]
[[Category: Guanylate kinase]]
[[Category: Plasmodium vivax]]
[[Category: Plasmodium vivax]]
[[Category: Single protein]]
[[Category: Le Trong I]]
[[Category: Merritt, E A.]]
[[Category: Merritt EA]]
[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
[[Category: Trong, I Le.]]
[[Category: kinase]]
[[Category: phosphotransferase]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: purine metabolism]]
[[Category: sgpp]]
[[Category: structural genomic]]
[[Category: structural genomics of pathogenic protozoa consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:43:38 2008''

Latest revision as of 08:34, 30 October 2024

Crystal structure of Plasmodium vivax guanylate kinase

2qor, resolution 1.80Å

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