5e56: Difference between revisions

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'''Unreleased structure'''


The entry 5e56 is ON HOLD
==Crystal structure of mouse CTLA-4==
<StructureSection load='5e56' size='340' side='right'caption='[[5e56]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5e56]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E56 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E56 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.504&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e56 OCA], [https://pdbe.org/5e56 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e56 RCSB], [https://www.ebi.ac.uk/pdbsum/5e56 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e56 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CTLA4_MOUSE CTLA4_MOUSE] Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28 (By similarity).


Authors: Fedorov, A.A., Fedorov, E.V., SAMANTA, D, BONNANO, J.B., ALMO, S.C.
==See Also==
 
*[[CTLA-4|CTLA-4]]
Description: Crystal structure of mouse CTLA-4
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Almo, S.C]]
[[Category: Large Structures]]
[[Category: Fedorov, A.A]]
[[Category: Mus musculus]]
[[Category: Samanta, D, Bonnano, J.B]]
[[Category: Almo SC]]
[[Category: Fedorov, E.V]]
[[Category: Bonanno JB]]
[[Category: Fedorov AA]]
[[Category: Fedorov EV]]
[[Category: SAMANTA D]]
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