2n0e: Difference between revisions
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==NMR structure of Neuromedin C in 40% TFE== | ==NMR structure of Neuromedin C in 40% TFE== | ||
<StructureSection load='2n0e' size='340' side='right' caption='[[2n0e | <StructureSection load='2n0e' size='340' side='right'caption='[[2n0e]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2n0e]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N0E OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[2n0e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N0E FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n0e OCA], [https://pdbe.org/2n0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n0e RCSB], [https://www.ebi.ac.uk/pdbsum/2n0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n0e ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GRP_HUMAN GRP_HUMAN] GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Adrover M]] | ||
[[Category: | [[Category: Martorell G]] | ||
[[Category: | [[Category: Pauwels K]] | ||
[[Category: | [[Category: Perez J]] | ||
[[Category: | [[Category: Sanchis P]] | ||
[[Category: | [[Category: Vilanova B]] | ||
Latest revision as of 07:43, 9 October 2024
NMR structure of Neuromedin C in 40% TFE
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