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[[Image:2gsw.gif|left|200px]]


{{Structure
==Crystal Structure of the Putative NADPH-dependent Azobenzene FMN-Reductase YhdA from Bacillus subtilis, Northeast Structural Genomics Target SR135==
|PDB= 2gsw |SIZE=350|CAPTION= <scene name='initialview01'>2gsw</scene>, resolution 2.92&Aring;
<StructureSection load='2gsw' size='340' side='right'caption='[[2gsw]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Fmn+Binding+Site+For+Residue+A+201'>AC1</scene>, <scene name='pdbsite=AC2:Fmn+Binding+Site+For+Residue+B+202'>AC2</scene>, <scene name='pdbsite=AC3:Fmn+Binding+Site+For+Residue+C+203'>AC3</scene> and <scene name='pdbsite=AC4:Fmn+Binding+Site+For+Residue+D+204'>AC4</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[2gsw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GSW FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.92&#8491;</td></tr>
|GENE= yhdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 Bacillus subtilis subsp. subtilis str. 168])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03358 FMN_red]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsw OCA], [https://pdbe.org/2gsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gsw RCSB], [https://www.ebi.ac.uk/pdbsum/2gsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gsw ProSAT], [https://www.topsan.org/Proteins/NESGC/2gsw TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsw OCA], [http://www.ebi.ac.uk/pdbsum/2gsw PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2gsw RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/AZR_BACSU AZR_BACSU] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity.<ref>PMID:16752898</ref> <ref>PMID:16861800</ref>
'''Crystal Structure of the Putative NADPH-dependent Azobenzene FMN-Reductase YhdA from Bacillus subtilis, Northeast Structural Genomics Target SR135'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
2GSW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSW OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gsw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gsw ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Acton, T B.]]
[[Category: Acton TB]]
[[Category: Cooper, B.]]
[[Category: Cooper B]]
[[Category: Cunningham, K.]]
[[Category: Cunningham K]]
[[Category: Forouhar, F.]]
[[Category: Forouhar F]]
[[Category: Hunt, J F.]]
[[Category: Hunt JF]]
[[Category: Hussain, M.]]
[[Category: Hussain M]]
[[Category: Janjua, H.]]
[[Category: Janjua H]]
[[Category: Jayaraman, S.]]
[[Category: Jayaraman S]]
[[Category: Ma, L C.]]
[[Category: Ma L-C]]
[[Category: Montelione, G T.]]
[[Category: Montelione GT]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Shen J]]
[[Category: Shen, J.]]
[[Category: Tong L]]
[[Category: Tong, L.]]
[[Category: Xiao R]]
[[Category: Xiao, R.]]
[[Category: alpha-beta protein]]
[[Category: nesg]]
[[Category: northeast structural genomics consortium]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: unknown function]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 10:01:27 2008''
Retrieved from "https://proteopedia.org/2gsw"