CD59: Difference between revisions

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== Function ==
== Function ==


'''CD59''' ('''Cluster of Differentiation 59''') is a protein which attaches to host cells via a GPI anchor.  CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9.
'''CD59''' ('''Cluster of Differentiation 59''') is a protein which attaches to host cells via a GPI anchor.  CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9. <ref>PMID:1698710</ref>


== Relevance ==
== Relevance ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


[[1erg]], [[1erh]], [[1cdq]], [[1cdr]], [[1cds]] – hCD59 extracellular domain – human - NMR<br />
[[1erg]], [[1erh]], [[1cdq]], [[1cdr]], [[1cds]] – hCD59 extracellular domain 26-102 – human - NMR<br />
[[2ofs]], [[2j8b]], [[2uwr]], [[2ux2]] – hCD59 extracellular domain <br />
[[2ofs]], [[2j8b]], [[2uwr]], [[2ux2]] – hCD59 extracellular domain <br />
[[4bik]] – hCD59 extracellular domain + intermedilysin<br />
[[8cn6]] – hCD59 extracellular domain + cyclic peptide<br />
[[4bik]], [[5imt]] – hCD59 extracellular domain + intermedilysin<br />
[[5imy]] – hCD59 extracellular domain + vaginolysin<br />
[[6zd0]] – hCD59 extracellular domain + cytolysin – Cryo EM<br />
[[8b0f]] – hCD59 extracellular domain + C5b8 – Cryo EM<br />
[[8b0g]], [[8b0h]] – hCD59 extracellular domain + C5b9 + 2C9 – Cryo EM<br />
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 08:54, 20 January 2025

Structure of human CD59 extracellular domain (green) complex with intermedilysin (cyan) (PDB entry 4bik)

Drag the structure with the mouse to rotate

3D structures of CD59

Updated on 20-January-2025

1erg, 1erh, 1cdq, 1cdr, 1cds – hCD59 extracellular domain 26-102 – human - NMR
2ofs, 2j8b, 2uwr, 2ux2 – hCD59 extracellular domain
8cn6 – hCD59 extracellular domain + cyclic peptide
4bik, 5imt – hCD59 extracellular domain + intermedilysin
5imy – hCD59 extracellular domain + vaginolysin
6zd0 – hCD59 extracellular domain + cytolysin – Cryo EM
8b0f – hCD59 extracellular domain + C5b8 – Cryo EM
8b0g, 8b0h – hCD59 extracellular domain + C5b9 + 2C9 – Cryo EM

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky