4znq: Difference between revisions

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'''Unreleased structure'''


The entry 4znq is ON HOLD  until Paper Publication
==Crystal structure of Dln1 complexed with Man(alpha1-2)Man==
 
<StructureSection load='4znq' size='340' side='right'caption='[[4znq]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
Authors: Jia, N., Jiang, Y.L., Cheng, W., Wang, H.W., Zhou, C.Z., Chen, Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4znq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZNQ FirstGlance]. <br>
Description: Crystal structure of Dln1 complexed with Man(alpha1-2)Man
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PRD_900111:2alpha-alpha-mannobiose'>PRD_900111</scene></td></tr>
[[Category: Chen, Y]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4znq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4znq OCA], [https://pdbe.org/4znq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4znq RCSB], [https://www.ebi.ac.uk/pdbsum/4znq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4znq ProSAT]</span></td></tr>
[[Category: Jia, N]]
</table>
[[Category: Wang, H.W]]
== Function ==
[[Category: Jiang, Y.L]]
[https://www.uniprot.org/uniprot/AEP1_DANRE AEP1_DANRE] Pore-forming protein which might play a role in host defense. Exists as an antiparallel dimer in solution. Can also assemble into an octameric pore-like structure spanning the cell membrane. Oligomerization may be triggered by binding of the jacalin-type lectin domain to high-mannose cell-surface proteoglycans, and also requires a low pH environment. In vitro, shows high binding affinity for S.cerevisiae mannan and human HIV virus glycoprotein gp120.<ref>PMID:26711430</ref>
[[Category: Cheng, W]]
== References ==
[[Category: Zhou, C.Z]]
<references/>
__TOC__
</StructureSection>
[[Category: Danio rerio]]
[[Category: Large Structures]]
[[Category: Chen Y]]
[[Category: Cheng W]]
[[Category: Jia N]]
[[Category: Jiang YL]]
[[Category: Wang HW]]
[[Category: Zhou CZ]]
Retrieved from "https://proteopedia.org/4znq"