4zra: Difference between revisions

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'''Unreleased structure'''


The entry 4zra is ON HOLD  until Paper Publication
==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE==
 
<StructureSection load='4zra' size='340' side='right'caption='[[4zra]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
Authors: Martinot, A.J., Farrow, M., Bai, L., Layre, E., Cheng, T.Y., Tsai, J.H.C., Iqbal, J., Annand, J., Sullivan, Z., Hussain, M., Sacchettini, J., Moody, D.B., Seeliger, J., Rubin, E.J., TB Structural Genomics Consortium (TBSGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4zra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZRA FirstGlance]. <br>
Description: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4RF:TRIPALMITOYLGLYCEROL'>4RF</scene></td></tr>
[[Category: Hussain, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zra OCA], [https://pdbe.org/4zra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zra RCSB], [https://www.ebi.ac.uk/pdbsum/4zra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zra ProSAT]</span></td></tr>
[[Category: Tsai, J.H.C]]
</table>
[[Category: Moody, D.B]]
== Function ==
[[Category: Layre, E]]
[https://www.uniprot.org/uniprot/LPRG_MYCTU LPRG_MYCTU] TLR2 agonist that can inhibit primary human macrophage MHC-II Ag processing. Required for Rv1410c (P55) activity.<ref>PMID:15294983</ref> <ref>PMID:18156250</ref>
[[Category: Bai, L]]
== References ==
[[Category: Farrow, M]]
<references/>
[[Category: Rubin, E.J]]
__TOC__
[[Category: Annand, J]]
</StructureSection>
[[Category: Cheng, T.Y]]
[[Category: Large Structures]]
[[Category: Sullivan, Z]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Seeliger, J]]
[[Category: Annand J]]
[[Category: Iqbal, J]]
[[Category: Bai L]]
[[Category: Martinot, A.J]]
[[Category: Cheng TY]]
[[Category: Sacchettini, J]]
[[Category: Farrow M]]
[[Category: Tb Structural Genomics Consortium (Tbsgc)]]
[[Category: Hussain M]]
[[Category: Iqbal J]]
[[Category: Layre E]]
[[Category: Martinot AJ]]
[[Category: Moody DB]]
[[Category: Rubin EJ]]
[[Category: Sacchettini J]]
[[Category: Seeliger J]]
[[Category: Sullivan Z]]
[[Category: Tsai JHC]]
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