5ebv: Difference between revisions

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New page: '''Unreleased structure''' The entry 5ebv is ON HOLD until Paper Publication Authors: Gajadeera, C.S., Hou, C., Garneau-Tsodikova, S., Tsodikov, O.V. Description: [[Category: Unreleas...
 
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'''Unreleased structure'''


The entry 5ebv is ON HOLD  until Paper Publication
==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA==
 
<StructureSection load='5ebv' size='340' side='right'caption='[[5ebv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Gajadeera, C.S., Hou, C., Garneau-Tsodikova, S., Tsodikov, O.V.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ebv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EBV FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5LR:5-(4-CHLOROPHENYL)-~{N}-[3-(3,4-DIHYDRO-1~{H}-ISOQUINOLIN-2-YL)PROPYL]-4-METHYL-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
[[Category: Tsodikov, O.V]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ebv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ebv OCA], [https://pdbe.org/5ebv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ebv RCSB], [https://www.ebi.ac.uk/pdbsum/5ebv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ebv ProSAT]</span></td></tr>
[[Category: Hou, C]]
</table>
[[Category: Garneau-Tsodikova, S]]
== Function ==
[[Category: Gajadeera, C.S]]
[https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Gajadeera CS]]
[[Category: Garneau-Tsodikova S]]
[[Category: Hou C]]
[[Category: Tsodikov OV]]