5ebv: Difference between revisions
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==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA== | |||
<StructureSection load='5ebv' size='340' side='right'caption='[[5ebv]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ebv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EBV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5LR:5-(4-CHLOROPHENYL)-~{N}-[3-(3,4-DIHYDRO-1~{H}-ISOQUINOLIN-2-YL)PROPYL]-4-METHYL-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ebv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ebv OCA], [https://pdbe.org/5ebv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ebv RCSB], [https://www.ebi.ac.uk/pdbsum/5ebv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ebv ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Garneau-Tsodikova | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Gajadeera CS]] | |||
[[Category: Garneau-Tsodikova S]] | |||
[[Category: Hou C]] | |||
[[Category: Tsodikov OV]] | |||
Latest revision as of 12:27, 6 March 2024
Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA
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