5eqj: Difference between revisions
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==Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae== | |||
<StructureSection load='5eqj' size='340' side='right'caption='[[5eqj]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5eqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqj OCA], [https://pdbe.org/5eqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqj RCSB], [https://www.ebi.ac.uk/pdbsum/5eqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqj ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRM6_YEAST TRM6_YEAST] Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Binds RNA. Also required for repression of GCN4 mRNA translation by the upstream open reading frames (uORFs) under conditions of amino acid sufficiency.<ref>PMID:10779558</ref> <ref>PMID:7542616</ref> <ref>PMID:9851972</ref> | |||
==See Also== | |||
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: Jiang | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: | [[Category: Fan X]] | ||
[[Category: Wang | [[Category: Jiang X]] | ||
[[Category: | [[Category: Li X]] | ||
[[Category: Teng M]] | |||
[[Category: Wang C]] | |||
[[Category: Wang M]] | |||
[[Category: Zhu Y]] | |||
Latest revision as of 09:11, 20 March 2024
Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae
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