5ess: Difference between revisions

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New page: '''Unreleased structure''' The entry 5ess is ON HOLD Authors: Johnston, J.M., Jirgis, E.N.M., Bashiri, G., Bulloch, E.M.M., Baker, E.N. Description: [[Category: Unreleased Structures]...
 
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'''Unreleased structure'''


The entry 5ess is ON HOLD
==Crystal Structure of M. tuberculosis MenD bound to Mg2+ and covalent intermediate I (a ThDP and decarboxylated 2-oxoglutarate adduct)==
 
<StructureSection load='5ess' size='340' side='right'caption='[[5ess]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Johnston, J.M., Jirgis, E.N.M., Bashiri, G., Bulloch, E.M.M., Baker, E.N.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ess]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ESS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ESS FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TOG:4-[3-[(4-AZANYL-2-METHYL-PYRIMIDIN-5-YL)METHYL]-4-METHYL-5-[2-[OXIDANYL(PHOSPHONOOXY)PHOSPHORYL]OXYETHYL]-1,3-THIAZOL-3-IUM-2-YL]-4-OXIDANYL-BUTANOIC+ACID'>TOG</scene></td></tr>
[[Category: Johnston, J.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ess OCA], [https://pdbe.org/5ess PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ess RCSB], [https://www.ebi.ac.uk/pdbsum/5ess PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ess ProSAT]</span></td></tr>
[[Category: Bashiri, G]]
</table>
[[Category: Jirgis, E.N.M]]
== Function ==
[[Category: Bulloch, E.M.M]]
[https://www.uniprot.org/uniprot/MEND_MYCTU MEND_MYCTU] Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
[[Category: Baker, E.N]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Baker EN]]
[[Category: Bashiri G]]
[[Category: Bulloch EMM]]
[[Category: Jirgis ENM]]
[[Category: Johnston JM]]
Retrieved from "https://proteopedia.org/5ess"