5d21: Difference between revisions

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==Multivalency Effects in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting Lectin LecA==
==Multivalency Effects in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting Lectin LecA==
<StructureSection load='5d21' size='340' side='right' caption='[[5d21]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5d21' size='340' side='right'caption='[[5d21]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5d21]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D21 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5d21]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D21 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=56N:PHENYL+BETA-D-GALACTOPYRANOSIDE'>56N</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d21 OCA], [http://pdbe.org/5d21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d21 RCSB], [http://www.ebi.ac.uk/pdbsum/5d21 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=56N:PHENYL+BETA-D-GALACTOPYRANOSIDE'>56N</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d21 OCA], [https://pdbe.org/5d21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d21 RCSB], [https://www.ebi.ac.uk/pdbsum/5d21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d21 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bergmann, M]]
[[Category: Large Structures]]
[[Category: Darbre, T]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Jin, X]]
[[Category: Bergmann M]]
[[Category: Michaud, G]]
[[Category: Darbre T]]
[[Category: Reymond, J L]]
[[Category: Jin X]]
[[Category: Stocker, A]]
[[Category: Michaud G]]
[[Category: Visini, R]]
[[Category: Reymond J-L]]
[[Category: Antimicrobial]]
[[Category: Stocker A]]
[[Category: Biofilm]]
[[Category: Visini R]]
[[Category: Lectin]]
[[Category: Multivalency]]
[[Category: Pseudomona]]
[[Category: Sugar binding protein]]
Retrieved from "https://proteopedia.org/5d21"