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==X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A==
==X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A==
<StructureSection load='4x46' size='340' side='right' caption='[[4x46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4x46' size='340' side='right'caption='[[4x46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4x46]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X46 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4x46]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X46 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x46 OCA], [http://pdbe.org/4x46 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x46 RCSB], [http://www.ebi.ac.uk/pdbsum/4x46 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x46 OCA], [https://pdbe.org/4x46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x46 RCSB], [https://www.ebi.ac.uk/pdbsum/4x46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x46 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY]] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.  
[https://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Thymidine phosphorylase]]
[[Category: Large Structures]]
[[Category: Balaev, V V]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Betzel, C]]
[[Category: Balaev VV]]
[[Category: Gabdoulkhakov, A G]]
[[Category: Betzel C]]
[[Category: Lashkov, A A]]
[[Category: Gabdoulkhakov AG]]
[[Category: Mikhailov, A M]]
[[Category: Lashkov AA]]
[[Category: Prokofev, I I]]
[[Category: Mikhailov AM]]
[[Category: Metabolism]]
[[Category: Prokofev II]]
[[Category: Nucleoside]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4x46"