Clathrin: Difference between revisions

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<StructureSection load='3lvg' size='350' side='right' caption='Bovine clathrin heavy (darkmagenta, magenta, violet) and light (yellow, green, cyan) chains (PDB entry [[3lvg]])' scene='46/465441/Cv/1'>
<StructureSection load='3lvg' size='350' side='right' caption='Bovine clathrin heavy (darkmagenta, magenta, violet) and light (yellow, green, cyan) chains (PDB entry [[3lvg]])' scene='46/465441/Cv/1'>


'''Clathrin''' (CLT) is a component of vesicle coast.<ref>PMID:1063406</ref>  For details see [[Clathrin JMU]].
'''Clathrin''' (CLT) is a component of vesicle coats.<ref>PMID:1063406</ref>  For details see [[Clathrin JMU]].


== Structural highlights ==
== Structural highlights ==
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Clathrin is composed of <scene name='46/465441/Cv/2'>3 heavy chains (Hc) and 3 light chains (Lc) interacting in their C-termini and forming a triskelion</scene>. <ref>PMID:20493816</ref> The Hc domains are: N-terminal, ankle, distal leg, knee, proximal leg and trimerization.
Clathrin is composed of <scene name='46/465441/Cv/2'>3 heavy chains (Hc) and 3 light chains (Lc) interacting in their C-termini and forming a triskelion</scene>. <ref>PMID:20493816</ref> The Hc domains are: N-terminal, ankle, distal leg, knee, proximal leg and trimerization.


[[FirstGlance/Virus_Capsids_and_Other_Large_Assemblies#Clathrin_Coat|Clathrin Coat]] shows a small, empty clathrin coat assembly of triskelions from an electron microscopic structure, [[3iyv]].


</StructureSection>
== 3D Structures of Clathrin ==
== 3D Structures of Clathrin ==
[[Clathrin 3D structures]]


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
</StructureSection>
{{#tree:id=OrganizedByTopic|openlevels=0|
 
*clathrin
 
**[[1bpo]] – rCLT Hc N terminal domain + linker – rat<br />
**[[1b89]] – bCLT Hc proximal leg – bovine<br />
**[[3qil]] - bCLT Hc trimerization domain<br />
**[[3lvg]] - bCLT Hc + Lc<br />
**[[3lvh]] - bCLT Hc HUB fragment + Lc <br />
**[[1xi4]], [[3iyv]] – bCLT Hc + Lc – Cryo EM
 
*Clathrin binary complexes


**[[1c9i]], [[1c9l]] - rCLT Hc N terminal + B-adaptin 3<br />
**[[2xzg]], [[2xzh]], [[4g55]]- CLT Hc N terminal + pitstop inhibitor - human<br />
**[[1utc]] - bCLT Hc N terminal + amphiphysin peptide<br />
**[[1xi5]] - bCLT Hc + auxilin J-domain – Cryo EM<br />
**[[3gc3]] – bCLT Hc WD domain + b-arrestin-1<br />
**[[3gd1]] - bCLT Hc + Hc WD domain + b-arrest
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 21:09, 13 November 2022

Bovine clathrin heavy (darkmagenta, magenta, violet) and light (yellow, green, cyan) chains (PDB entry 3lvg)

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References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Eric Martz, Alexander Berchansky