5d5u: Difference between revisions

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==Crystal structure of human Hsf1 with HSE DNA==
==Crystal structure of human Hsf1 with HSE DNA==
<StructureSection load='5d5u' size='340' side='right' caption='[[5d5u]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
<StructureSection load='5d5u' size='340' side='right'caption='[[5d5u]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5d5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D5U FirstGlance]. <br>
<table><tr><td colspan='2'>[[5d5u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D5U FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5u OCA], [http://pdbe.org/5d5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d5u RCSB], [http://www.ebi.ac.uk/pdbsum/5d5u PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5u OCA], [https://pdbe.org/5d5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d5u RCSB], [https://www.ebi.ac.uk/pdbsum/5d5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d5u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref>
[https://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5d5u" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5d5u" style="background-color:#fffaf0;"></div>
==See Also==
*[[Heat shock factor|Heat shock factor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bracher, A]]
[[Category: Homo sapiens]]
[[Category: Double helix]]
[[Category: Large Structures]]
[[Category: Helix-turn-helix]]
[[Category: Bracher A]]
[[Category: Protein-dna complex]]
[[Category: Hartl FU]]
[[Category: Transcription-dna complex]]
[[Category: Hayer-Hartl M]]
[[Category: Neudegger T]]
[[Category: Verghese J]]
Retrieved from "https://proteopedia.org/5d5u"