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==GPN-loop GTPase Npa3 in complex with GMPPCP==
==GPN-loop GTPase Npa3 in complex with GMPPCP==
<StructureSection load='5hcn' size='340' side='right' caption='[[5hcn]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5hcn' size='340' side='right'caption='[[5hcn]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5hcn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HCN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HCN FirstGlance]. <br>
<table><tr><td colspan='2'>[[5hcn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HCN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hcn OCA], [http://pdbe.org/5hcn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hcn RCSB], [http://www.ebi.ac.uk/pdbsum/5hcn PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hcn OCA], [https://pdbe.org/5hcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hcn RCSB], [https://www.ebi.ac.uk/pdbsum/5hcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hcn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GPN1_YEAST GPN1_YEAST]] Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21844196). May act at an RNAP assembly step prior to nuclear import (PubMed:23267056). Promotes sister chromatid separation during anaphase (PubMed:21532343).<ref>PMID:15082539</ref> <ref>PMID:20855544</ref> <ref>PMID:21532343</ref> <ref>PMID:21844196</ref> <ref>PMID:23267056</ref>
[https://www.uniprot.org/uniprot/GPN1_YEAST GPN1_YEAST] Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21844196). May act at an RNAP assembly step prior to nuclear import (PubMed:23267056). Promotes sister chromatid separation during anaphase (PubMed:21532343).<ref>PMID:15082539</ref> <ref>PMID:20855544</ref> <ref>PMID:21532343</ref> <ref>PMID:21844196</ref> <ref>PMID:23267056</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cramer, P]]
[[Category: Large Structures]]
[[Category: Kostrewa, D]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Muehlbacher, W]]
[[Category: Cramer P]]
[[Category: Niesser, J]]
[[Category: Kostrewa D]]
[[Category: Wagner, F R]]
[[Category: Muehlbacher W]]
[[Category: Assembly]]
[[Category: Niesser J]]
[[Category: Chaperone]]
[[Category: Wagner FR]]
[[Category: Gpn-loop gtpase]]
[[Category: Hydrolase]]
[[Category: Rna polymerase]]
Retrieved from "https://proteopedia.org/5hcn"