Fibrin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
 
(7 intermediate revisions by one other user not shown)
Line 1: Line 1:
{{STRUCTURE_1n73|  PDB=1n73 | SIZE=350| SCENE=Fibrin/Cv/2 |right|CAPTION=Fibrin α1 subunit (red, yellow), β subunit (Green, blue), γ subunit (orange, magenta) from ''Petromyzon marinus'', [[1n73]] }}
<StructureSection load='1n73' size='350' side='right' scene='41/417472/Cv/3' caption='Fibrin α1 subunit (red, yellow), β subunit (cyan, blue), γ subunit (orange, magenta) from Petromyzon marinus (PDB entry [[1n73]])'>
 
== Function ==
== Function ==


Line 8: Line 9:
Overexpression of FIa can cause thrombosis.
Overexpression of FIa can cause thrombosis.


== Structural highlights ==
<scene name='41/417472/Cv/6'>Ca coordination site in β subunit</scene>.
<scene name='41/417472/Cv/7'>Ca coordination site in γ subunit</scene> (PDB entry [[1n73]]).
</StructureSection>
== 3D Structures of Fibrin ==
== 3D Structures of Fibrin ==


Line 16: Line 23:
[[2hlo]], [[1n86]] - hFIa α, β, γ chains + peptide<br />
[[2hlo]], [[1n86]] - hFIa α, β, γ chains + peptide<br />
[[1n8e]] - hFIa α, β, γ chains <br />
[[1n8e]] - hFIa α, β, γ chains <br />
[[2a45]] - hFIa α, β, γ chains + thrombin<br />
[[1fzc]] – hDDFIa+peptide<br />
[[1n73]] - FIa α, β, γ chains + peptide – Sea lamprey<br />
[[1n73]] - FIa α, β, γ chains + peptide – Sea lamprey<br />
[[1fzc]] – hDDFIa+peptide<br />


== References ==
== References ==