1se4: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
New page: left|200px<br /> <applet load="1se4" size="450" color="white" frame="true" align="right" spinBox="true" caption="1se4, resolution 1.9Å" /> '''STAPHYLOCOCCAL ENTER...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(21 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1se4.gif|left|200px]]<br />
<applet load="1se4" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1se4, resolution 1.9&Aring;" />
'''STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE'''<br />


==Overview==
==STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE==
The three-dimensional structure of staphylococcal enterotoxin C2 has been, determined at 2.7 A resolution by x-ray diffraction, while the structures, of enterotoxins A and E have been modelled based on their sequence, homology to other staphylococcal enterotoxins. The T-cell receptor-binding, sites of staphylococcal enterotoxin (SE) B and SEC2 are compared and the, stereochemical interactions likely to be responsible for their differing V, beta specificities are identified. A similar comparison is made between, SEA and SEE.
<StructureSection load='1se4' size='340' side='right'caption='[[1se4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1se4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SE4 FirstGlance]. <br>
1SE4 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]] with LAT as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SE4 OCA]].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900004:beta-lactose'>PRD_900004</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1se4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1se4 OCA], [https://pdbe.org/1se4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1se4 RCSB], [https://www.ebi.ac.uk/pdbsum/1se4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1se4 ProSAT]</span></td></tr>
Residues defining V beta specificity in staphylococcal enterotoxins., Swaminathan S, Furey W, Pletcher J, Sax M, Nat Struct Biol. 1995 Aug;2(8):680-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7552730 7552730]
</table>
[[Category: Single protein]]
== Function ==
[https://www.uniprot.org/uniprot/ETXB_STAAU ETXB_STAAU] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/se/1se4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1se4 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Sax, M.]]
[[Category: Sax M]]
[[Category: Swaminathan, S.]]
[[Category: Swaminathan S]]
[[Category: LAT]]
[[Category: 3d structure]]
[[Category: complex]]
[[Category: lactose]]
[[Category: seb]]
[[Category: superantigen]]
[[Category: toxin]]
[[Category: x-ray]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:11:51 2007''

Latest revision as of 08:31, 1 May 2024

STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE

1se4, resolution 1.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1se4&oldid=4140327"