5huz: Difference between revisions
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==Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase== | |||
<StructureSection load='5huz' size='340' side='right'caption='[[5huz]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5huz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mxr 2mxr]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HUZ FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5huz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5huz OCA], [https://pdbe.org/5huz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5huz RCSB], [https://www.ebi.ac.uk/pdbsum/5huz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5huz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref> | |||
==See Also== | |||
*[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Alper SL]] | |||
[[Category: Anklin C]] | |||
[[Category: Birrane G]] | |||
[[Category: Pollak M]] | |||
[[Category: Rigby AC]] | |||
[[Category: Sharma AK]] | |||