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==Crystal structure of Human Quinolinate Phosphoribosyltransferase==
==Crystal structure of Human Quinolinate Phosphoribosyltransferase==
<StructureSection load='5ayx' size='340' side='right' caption='[[5ayx]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5ayx' size='340' side='right'caption='[[5ayx]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ayx]] is a 6 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lar 3lar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AYX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AYX FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ayx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lar 3lar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AYX FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinate-nucleotide_diphosphorylase_(carboxylating) Nicotinate-nucleotide diphosphorylase (carboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.19 2.4.2.19] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ayx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ayx OCA], [http://pdbe.org/5ayx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ayx RCSB], [http://www.ebi.ac.uk/pdbsum/5ayx PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ayx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ayx OCA], [https://pdbe.org/5ayx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ayx RCSB], [https://www.ebi.ac.uk/pdbsum/5ayx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ayx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NADC_HUMAN NADC_HUMAN]] Involved in the catabolism of quinolinic acid (QA).<ref>PMID:17868694</ref>
[https://www.uniprot.org/uniprot/NADC_HUMAN NADC_HUMAN] Involved in the catabolism of quinolinic acid (QA).<ref>PMID:17868694</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ayx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ayx" style="background-color:#fffaf0;"></div>
==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: An, J Y]]
[[Category: Homo sapiens]]
[[Category: Eom, S H]]
[[Category: Large Structures]]
[[Category: Fukuoka, S I]]
[[Category: An JY]]
[[Category: Im, Y J]]
[[Category: Eom SH]]
[[Category: Kang, G B]]
[[Category: Fukuoka S-I]]
[[Category: Kim, M K]]
[[Category: Im YJ]]
[[Category: Lee, J G]]
[[Category: Kang GB]]
[[Category: Lee, J H]]
[[Category: Kim M-K]]
[[Category: Youn, H S]]
[[Category: Lee J-G]]
[[Category: Nad biosynthesis]]
[[Category: Lee JH]]
[[Category: Nadc]]
[[Category: Youn H-S]]
[[Category: Quinolinate phosphoribosyltransferase]]
[[Category: Transferase]]