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==Crystal Structure of MtNAS in complex with MTA and tNA==
==Crystal Structure of MtNAS in complex with MTA and tNA==
<StructureSection load='3fpf' size='340' side='right' caption='[[3fpf]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
<StructureSection load='3fpf' size='340' side='right'caption='[[3fpf]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fpf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FPF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fpf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FPF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=TNA:N-[(3S)-3-{[(3S)-3-AMINO-3-CARBOXYPROPYL]AMINO}-3-CARBOXYPROPYL]-L-GLUTAMIC+ACID'>TNA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fpe|3fpe]], [[3fpg|3fpg]], [[3fph|3fph]], [[3fpj|3fpj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=TNA:N-[(3S)-3-{[(3S)-3-AMINO-3-CARBOXYPROPYL]AMINO}-3-CARBOXYPROPYL]-L-GLUTAMIC+ACID'>TNA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTH675 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fpf OCA], [https://pdbe.org/3fpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fpf RCSB], [https://www.ebi.ac.uk/pdbsum/3fpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fpf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fpf OCA], [http://pdbe.org/3fpf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fpf RCSB], [http://www.ebi.ac.uk/pdbsum/3fpf PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O26771_METTH O26771_METTH]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/3fpf_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/3fpf_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Metth]]
[[Category: Large Structures]]
[[Category: Arnoux, P]]
[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
[[Category: Dreyfus, C]]
[[Category: Arnoux P]]
[[Category: Pignol, D]]
[[Category: Dreyfus C]]
[[Category: Biosynthetic protein]]
[[Category: Pignol D]]
[[Category: Nicotianamine]]
[[Category: Thermonicotianamine]]
[[Category: Transferase]]

Latest revision as of 09:52, 6 November 2024

Crystal Structure of MtNAS in complex with MTA and tNA

3fpf, resolution 1.66Å

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