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==THE NUCLEASE DOMAIN OF ADENO-ASSOCIATED VIRUS REP COMPLEXED WITH THE RBE' STEMLOOP OF THE VIRAL INVERTED TERMINAL REPEAT==
 
<StructureSection load='1uut' size='340' side='right' caption='[[1uut]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
==The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat==
<StructureSection load='1uut' size='340' side='right'caption='[[1uut]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uut]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Adeno-associated_virus_-_5 Adeno-associated virus - 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UUT FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uut]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Adeno-associated_virus_5 Adeno-associated virus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UUT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m55|1m55]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uut OCA], [http://pdbe.org/1uut PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uut RCSB], [http://www.ebi.ac.uk/pdbsum/1uut PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uut OCA], [https://pdbe.org/1uut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uut RCSB], [https://www.ebi.ac.uk/pdbsum/1uut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uut ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9YJC1_9VIRU Q9YJC1_9VIRU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uu/1uut_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uu/1uut_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adeno-associated virus - 5]]
[[Category: Adeno-associated virus 5]]
[[Category: Dyda, F]]
[[Category: Large Structures]]
[[Category: Hickman, A B]]
[[Category: Dyda F]]
[[Category: Kotin, R M]]
[[Category: Hickman AB]]
[[Category: Perez, Z N]]
[[Category: Kotin RM]]
[[Category: Ronning, D R]]
[[Category: Perez ZN]]
[[Category: Helicase]]
[[Category: Ronning DR]]
[[Category: Hydrolase-dna complex]]
[[Category: Hydrolase/dna]]
[[Category: Nuclease]]
[[Category: Nuclease-complex]]
[[Category: Protein-dna]]
[[Category: Replication]]
[[Category: Stemloop]]
[[Category: Viral protein]]

Latest revision as of 12:59, 13 December 2023

The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat

1uut, resolution 2.00Å

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