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==MANGANESE SUPEROXIDE DISMUTASE (MN-SOD) FROM DEINOCOCCUS RADIODURANS==
 
<StructureSection load='2cdy' size='340' side='right' caption='[[2cdy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
==Manganese Superoxide Dismutase (Mn-SOD) from Deinococcus radiodurans==
<StructureSection load='2cdy' size='340' side='right'caption='[[2cdy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cdy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDY FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cdy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CDY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1y67|1y67]], [[2ce4|2ce4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdy OCA], [https://pdbe.org/2cdy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cdy RCSB], [https://www.ebi.ac.uk/pdbsum/2cdy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cdy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdy OCA], [http://pdbe.org/2cdy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cdy RCSB], [http://www.ebi.ac.uk/pdbsum/2cdy PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODM_DEIRA SODM_DEIRA] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/2cdy_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/2cdy_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Superoxide Dismutase|Superoxide Dismutase]]
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Deira]]
[[Category: Deinococcus radiodurans R1]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Dennis, R]]
[[Category: Dennis R]]
[[Category: Gordon, E]]
[[Category: Gordon E]]
[[Category: Leonard, G]]
[[Category: Leonard G]]
[[Category: Mccarthy, J]]
[[Category: McCarthy J]]
[[Category: Mcsweeney, S]]
[[Category: McSweeney S]]
[[Category: Micossi, E]]
[[Category: Micossi E]]
[[Category: Moe, E]]
[[Category: Moe E]]
[[Category: Deinococcus radioduran]]
[[Category: Manganese superoxide dismutase]]
[[Category: Oxidoreductase]]
[[Category: Radiation resistance]]