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==CRYSTAL STRUCTURE OF E. COLI TDCF WITH BOUND ETHYLENE GLYCOL==
 
<StructureSection load='2uyj' size='340' side='right' caption='[[2uyj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
==Crystal structure of E. coli TdcF with bound ethylene glycol==
<StructureSection load='2uyj' size='340' side='right'caption='[[2uyj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2uyj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2uyj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UYJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2uyk|2uyk]], [[2uyn|2uyn]], [[2uyp|2uyp]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyj OCA], [https://pdbe.org/2uyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uyj RCSB], [https://www.ebi.ac.uk/pdbsum/2uyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyj OCA], [http://pdbe.org/2uyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uyj RCSB], [http://www.ebi.ac.uk/pdbsum/2uyj PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TDCF_ECOLI TDCF_ECOLI]] May be a post-translational regulator that controls the metabolic fate of L-threonine or the potentially toxic intermediate 2-ketobutyrate.  
[https://www.uniprot.org/uniprot/TDCF_ECOLI TDCF_ECOLI] May be a post-translational regulator that controls the metabolic fate of L-threonine or the potentially toxic intermediate 2-ketobutyrate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyj_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyj_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Burman, J D]]
[[Category: Large Structures]]
[[Category: Lawson, D M]]
[[Category: Burman JD]]
[[Category: Sawers, R G]]
[[Category: Lawson DM]]
[[Category: Stevenson, C E.M]]
[[Category: Sawers RG]]
[[Category: 2-ketobutyrate]]
[[Category: Stevenson CEM]]
[[Category: Ethylene glycol]]
[[Category: Ligand binding]]
[[Category: Tdcf protein]]
[[Category: Unknown function]]
[[Category: Yjgf/yer057c/uk114 family]]