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==Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase (NADH Form)==
==Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase (NADH Form)==
<StructureSection load='3adp' size='340' side='right' caption='[[3adp]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3adp' size='340' side='right'caption='[[3adp]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3adp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3a97 3a97] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ep9 2ep9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ADP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ADP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3adp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3a97 3a97] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ep9 2ep9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ADP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ADP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ado|3ado]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRYL1, GUL3DH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 European rabbit])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3adp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3adp OCA], [https://pdbe.org/3adp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3adp RCSB], [https://www.ebi.ac.uk/pdbsum/3adp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3adp ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-gulonate_3-dehydrogenase L-gulonate 3-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.45 1.1.1.45] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3adp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3adp OCA], [http://pdbe.org/3adp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3adp RCSB], [http://www.ebi.ac.uk/pdbsum/3adp PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CRYL1_RABIT CRYL1_RABIT]] Functions as crystallin in the rabbit eye lens. Has high L-gulonate 3-dehydrogenase activity.  
[https://www.uniprot.org/uniprot/CRYL1_RABIT CRYL1_RABIT] Functions as crystallin in the rabbit eye lens. Has high L-gulonate 3-dehydrogenase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/3adp_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/3adp_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: European rabbit]]
[[Category: Large Structures]]
[[Category: L-gulonate 3-dehydrogenase]]
[[Category: Oryctolagus cuniculus]]
[[Category: Asada, Y]]
[[Category: Asada Y]]
[[Category: Hara, A]]
[[Category: Hara A]]
[[Category: Kunishima, N]]
[[Category: Kunishima N]]
[[Category: Structural genomic]]
[[Category: Eye lens protein]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Rsgi]]
Retrieved from "https://proteopedia.org/3adp"