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==DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES==
==DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES==
<StructureSection load='1ncv' size='340' side='right' caption='[[1ncv]], [[NMR_Ensembles_of_Models | 7 NMR models]]' scene=''>
<StructureSection load='1ncv' size='340' side='right'caption='[[1ncv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ncv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NCV FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ncv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NCV FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ncv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ncv OCA], [http://pdbe.org/1ncv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ncv RCSB], [http://www.ebi.ac.uk/pdbsum/1ncv PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 7 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ncv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ncv OCA], [https://pdbe.org/1ncv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ncv RCSB], [https://www.ebi.ac.uk/pdbsum/1ncv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ncv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CCL7_HUMAN CCL7_HUMAN]] Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.  
[https://www.uniprot.org/uniprot/CCL7_HUMAN CCL7_HUMAN] Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1ncv_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1ncv_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]]
*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]]
*[[User:Coline Perrin/CCL2|User:Coline Perrin/CCL2]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Bernassau, J M]]
[[Category: Large Structures]]
[[Category: Darbon, H]]
[[Category: Bernassau JM]]
[[Category: Ferrara, P]]
[[Category: Darbon H]]
[[Category: Guillemot, J C]]
[[Category: Ferrara P]]
[[Category: Meunier, S]]
[[Category: Guillemot JC]]
[[Category: Beta-chemokine]]
[[Category: Meunier S]]
[[Category: Chemotaxis]]
[[Category: Cytokine]]
[[Category: Glycoprotein]]
[[Category: Heparin-binding]]
[[Category: Mcp-3]]
Retrieved from "https://proteopedia.org/1ncv"