1d76: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1d76.gif|left|200px]]


{{Structure
==CRYSTAL AND MOLECULAR STRUCTURE OF A DNA FRAGMENT CONTAINING A 2-AMINO ADENINE MODIFICATION: THE RELATIONSHIP BETWEEN CONFORMATION, PACKING, AND HYDRATION IN Z-DNA HEXAMERS==
|PDB= 1d76 |SIZE=350|CAPTION= <scene name='initialview01'>1d76</scene>, resolution 1.300&Aring;
<StructureSection load='1d76' size='340' side='right'caption='[[1d76]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DU:2&#39;-DEOXYURIDINE-5&#39;-MONOPHOSPHATE'>DU</scene>
<table><tr><td colspan='2'>[[1d76]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D76 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d76 OCA], [https://pdbe.org/1d76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d76 RCSB], [https://www.ebi.ac.uk/pdbsum/1d76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d76 ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d76 OCA], [http://www.ebi.ac.uk/pdbsum/1d76 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d76 RCSB]</span>
__TOC__
}}
</StructureSection>
 
[[Category: Large Structures]]
'''CRYSTAL AND MOLECULAR STRUCTURE OF A DNA FRAGMENT CONTAINING A 2-AMINO ADENINE MODIFICATION: THE RELATIONSHIP BETWEEN CONFORMATION, PACKING, AND HYDRATION IN Z-DNA HEXAMERS'''
[[Category: Berman HM]]
 
[[Category: Gaffney B]]
 
[[Category: Ginell SL]]
==Overview==
[[Category: Jones R]]
The crystal and molecular structure of d(CGUA'CG)2 (where A' is 2-aminoadenine) has been determined and refined to an R factor of 13.8% for data 8.0-1.3 A. The structure is very similar to the original Z-DNA structures with the sequence d(CGCGCG)2 [Gessner, R. V., Frederick, C. A., Quigley, G. J., Rich, A., &amp; Wang, A. H.-J. (1989) J. Biol. Chem. 264, 7921] and shows that the substitution of 2-aminoadenine-uracil base pairs in the two central steps is consistent with Z-DNA formation. In addition, we show how waters mediating intermolecular interactions may help to explain the ZI-ZII conformational pattern found in many Z-DNA structures.
[[Category: Schneider B]]
 
==About this Structure==
1D76 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D76 OCA].
 
==Reference==
Crystal and molecular structure of a DNA fragment containing a 2-aminoadenine modification: the relationship between conformation, packing, and hydration in Z-DNA hexamers., Schneider B, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1992 Oct 13;31(40):9622-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1390739 1390739]
[[Category: Protein complex]]
[[Category: Berman, H M.]]
[[Category: Gaffney, B.]]
[[Category: Ginell, S L.]]
[[Category: Jones, R.]]
[[Category: Schneider, B.]]
[[Category: double helix]]
[[Category: modified]]
[[Category: z-dna]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:36:00 2008''
Retrieved from "https://proteopedia.org/1d76"