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| [[Image:1d98.gif|left|200px]]
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| {{Structure
| | ==THE STRUCTURE OF AN OLIGO(DA).OLIGO(DT) TRACT AND ITS BIOLOGICAL IMPLICATIONS== |
| |PDB= 1d98 |SIZE=350|CAPTION= <scene name='initialview01'>1d98</scene>, resolution 2.500Å
| | <StructureSection load='1d98' size='340' side='right'caption='[[1d98]], [[Resolution|resolution]] 2.50Å' scene=''> |
| |SITE=
| | == Structural highlights == |
| |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>
| | <table><tr><td colspan='2'>[[1d98]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D98 FirstGlance]. <br> |
| |ACTIVITY=
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| |GENE=
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d98 OCA], [https://pdbe.org/1d98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d98 RCSB], [https://www.ebi.ac.uk/pdbsum/1d98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d98 ProSAT]</span></td></tr> |
| |DOMAIN=
| | </table> |
| |RELATEDENTRY=
| | __TOC__ |
| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d98 OCA], [http://www.ebi.ac.uk/pdbsum/1d98 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d98 RCSB]</span>
| | </StructureSection> |
| }}
| | [[Category: Large Structures]] |
| | | [[Category: Finch JT]] |
| '''THE STRUCTURE OF AN OLIGO(DA).OLIGO(DT) TRACT AND ITS BIOLOGICAL IMPLICATIONS'''
| | [[Category: Klug A]] |
| | | [[Category: Luisi BF]] |
| | | [[Category: Nelson HCM]] |
| ==Overview==
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| Poly(dA).poly(dT) has unusual properties in that it cannot associate into nucleosomes and short, phased runs of it cause DNA bending. The crystal structure of a B-type DNA dodecamer containing a homopolymeric run of six A.T base pairs shows that this region possesses special structural features, including a system of bifurcated hydrogen bonds, which explains some of the properties of this simple homopolymer.
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| ==About this Structure==
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| 1D98 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D98 OCA].
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| ==Reference==
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| The structure of an oligo(dA).oligo(dT) tract and its biological implications., Nelson HC, Finch JT, Luisi BF, Klug A, Nature. 1987 Nov 19-25;330(6145):221-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/3670410 3670410]
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| [[Category: Protein complex]] | |
| [[Category: Finch, J T.]] | |
| [[Category: Klug, A.]] | |
| [[Category: Luisi, B F.]] | |
| [[Category: Nelson, H C.M.]] | |
| [[Category: b-dna]]
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| [[Category: double helix]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:37:02 2008''
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