2z84: Difference between revisions

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==Insights from crystal and solution structures of mouse UfSP1==
==Insights from crystal and solution structures of mouse UfSP1==
<StructureSection load='2z84' size='340' side='right' caption='[[2z84]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2z84' size='340' side='right'caption='[[2z84]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2z84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z84 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2z84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z84 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z84 OCA], [http://pdbe.org/2z84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z84 RCSB], [http://www.ebi.ac.uk/pdbsum/2z84 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z84 OCA], [https://pdbe.org/2z84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z84 RCSB], [https://www.ebi.ac.uk/pdbsum/2z84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z84 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UFSP1_MOUSE UFSP1_MOUSE]] Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.<ref>PMID:17182609</ref>
[https://www.uniprot.org/uniprot/UFSP1_MOUSE UFSP1_MOUSE] Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.<ref>PMID:17182609</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z84_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z84_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Ahn, H C]]
[[Category: Mus musculus]]
[[Category: Chung, C H]]
[[Category: Ahn HC]]
[[Category: Ha, B H]]
[[Category: Chung CH]]
[[Category: Kang, S H]]
[[Category: Ha BH]]
[[Category: Kim, E E]]
[[Category: Kang SH]]
[[Category: Tanaka, K]]
[[Category: Kim EE]]
[[Category: Alpha/beta]]
[[Category: Tanaka K]]
[[Category: Hydrolase]]
[[Category: Papain like fold]]
[[Category: Protease]]
[[Category: Thiol protease]]
[[Category: Ubl conjugation pathway]]
Retrieved from "https://proteopedia.org/2z84"