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| [[Image:1dnm.gif|left|200px]]
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| {{Structure
| | ==CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)== |
| |PDB= 1dnm |SIZE=350|CAPTION= <scene name='initialview01'>1dnm</scene>, resolution 2.500Å
| | <StructureSection load='1dnm' size='340' side='right'caption='[[1dnm]], [[Resolution|resolution]] 2.50Å' scene=''> |
| |SITE=
| | == Structural highlights == |
| |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>
| | <table><tr><td colspan='2'>[[1dnm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNM FirstGlance]. <br> |
| |ACTIVITY=
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| |GENE=
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnm OCA], [https://pdbe.org/1dnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnm RCSB], [https://www.ebi.ac.uk/pdbsum/1dnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnm ProSAT]</span></td></tr> |
| |DOMAIN=
| | </table> |
| |RELATEDENTRY=
| | __TOC__ |
| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnm OCA], [http://www.ebi.ac.uk/pdbsum/1dnm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dnm RCSB]</span>
| | </StructureSection> |
| }}
| | [[Category: Large Structures]] |
| | | [[Category: Li BF]] |
| '''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''
| | [[Category: Neidle S]] |
| | | [[Category: Sanderson MR]] |
| | | [[Category: Skelly JV]] |
| ==Overview==
| | [[Category: Swann PF]] |
| The crystal structure of the dodecanucleotide d(CGCAAGCTGGCG) has been determined to a resolution of 2.5 A and refined to an R factor of 19.3% for 1710 reflections. The sequence crystallizes as a B-type double helix, with two G(anti).A(syn) base pairs. These are stabilized by three-center hydrogen bonds to pyrimidines that induce perturbations in base-pair geometry. The central AGCT region of the helix has a wide (greater than 6 A) minor groove.
| | [[Category: Tickle IJ]] |
| | | [[Category: Webster GD]] |
| ==About this Structure==
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| 1DNM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA].
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| ==Reference==
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| Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2395870 2395870]
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| [[Category: Protein complex]] | |
| [[Category: Li, B F.]] | |
| [[Category: Neidle, S.]] | |
| [[Category: Sanderson, M R.]] | |
| [[Category: Skelly, J V.]] | |
| [[Category: Swann, P F.]] | |
| [[Category: Tickle, I J.]] | |
| [[Category: Webster, G D.]] | |
| [[Category: b-dna]]
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| [[Category: double helix]]
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| [[Category: mismatched]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:45:00 2008''
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