2wci: Difference between revisions
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==Structure of E. coli monothiol glutaredoxin GRX4 homodimer== | ==Structure of E. coli monothiol glutaredoxin GRX4 homodimer== | ||
<StructureSection load='2wci' size='340' side='right' caption='[[2wci]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2wci' size='340' side='right'caption='[[2wci]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wci]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2wci]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WCI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wci OCA], [https://pdbe.org/2wci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wci RCSB], [https://www.ebi.ac.uk/pdbsum/2wci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wci ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GLRX4_ECOLI GLRX4_ECOLI] Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (Probable). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wci_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wci_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Chauvat | [[Category: Large Structures]] | ||
[[Category: Ferrer | [[Category: Chauvat F]] | ||
[[Category: Iwema | [[Category: Ferrer J-L]] | ||
[[Category: Jacquamet | [[Category: Iwema T]] | ||
[[Category: Picchiocci | [[Category: Jacquamet L]] | ||
[[Category: Traore | [[Category: Picchiocci A]] | ||
[[Category: Traore DAK]] | |||
Latest revision as of 17:34, 8 September 2026
Structure of E. coli monothiol glutaredoxin GRX4 homodimer
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