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[[Image:1e5e.gif|left|200px]]


{{Structure
==METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE==
|PDB= 1e5e |SIZE=350|CAPTION= <scene name='initialview01'>1e5e</scene>, resolution 2.18&Aring;
<StructureSection load='1e5e' size='340' side='right'caption='[[1e5e]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
|SITE= <scene name='pdbsite=PLA:Plp+Binding+Site+Chain+A'>PLA</scene> and <scene name='pdbsite=PLB:Plp+Binding+Site+Chain+B'>PLB</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PPJ:N-(HYDROXY{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)NORVALINE'>PPJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[1e5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichomonas_vaginalis_G3 Trichomonas vaginalis G3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5E FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
|GENE= MGL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5722 Trichomonas vaginalis])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PPJ:N-(HYDROXY{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)NORVALINE'>PPJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5e OCA], [https://pdbe.org/1e5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5e RCSB], [https://www.ebi.ac.uk/pdbsum/1e5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5e ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5e OCA], [http://www.ebi.ac.uk/pdbsum/1e5e PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e5e RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/A2FEV4_TRIV3 A2FEV4_TRIV3]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5e ConSurf].
<div style="clear:both"></div>


'''METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE'''
==See Also==
 
*[[Methionine gamma-lyase 3D structures|Methionine gamma-lyase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1E5E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Trichomonas_vaginalis Trichomonas vaginalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5E OCA].
[[Category: Large Structures]]
[[Category: Methionine gamma-lyase]]
[[Category: Trichomonas vaginalis G3]]
[[Category: Single protein]]
[[Category: Coombs GH]]
[[Category: Trichomonas vaginalis]]
[[Category: Goodall G]]
[[Category: Coombs, G H.]]
[[Category: Lapthorn AJ]]
[[Category: Goodall, G.]]
[[Category: Mottram JC]]
[[Category: Lapthorn, A J.]]
[[Category: Mottram, J C.]]
[[Category: c-s gamma lyase]]
[[Category: plp-dependent enzyme]]
[[Category: propargylglycine]]
[[Category: trichomonas vaginali]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:55:32 2008''
Retrieved from "https://proteopedia.org/1e5e"