3i5q: Difference between revisions

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==Nup170(aa1253-1502) at 2.2 A, S.cerevisiae==
==Nup170(aa1253-1502) at 2.2 A, S.cerevisiae==
<StructureSection load='3i5q' size='340' side='right' caption='[[3i5q]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3i5q' size='340' side='right'caption='[[3i5q]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i5q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i5q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I5Q FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i4r|3i4r]], [[3i5p|3i5p]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.204&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NLE3, NUP170, YBL0725, YBL079W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5q OCA], [https://pdbe.org/3i5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i5q RCSB], [https://www.ebi.ac.uk/pdbsum/3i5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5q OCA], [http://pdbe.org/3i5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i5q RCSB], [http://www.ebi.ac.uk/pdbsum/3i5q PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NU170_YEAST NU170_YEAST]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP170 probably plays an important role in NPC assembly and organization. In addition it is required for chromosome transmission fidelity.<ref>PMID:9864357</ref> <ref>PMID:12403813</ref> <ref>PMID:14697200</ref> <ref>PMID:11290711</ref> <ref>PMID:12473689</ref>
[https://www.uniprot.org/uniprot/NU170_YEAST NU170_YEAST] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP170 probably plays an important role in NPC assembly and organization. In addition it is required for chromosome transmission fidelity.<ref>PMID:9864357</ref> <ref>PMID:12403813</ref> <ref>PMID:14697200</ref> <ref>PMID:11290711</ref> <ref>PMID:12473689</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5q_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5q_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Nucleoporin|Nucleoporin]]
*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Schwartz, T U]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Whittle, J R.R]]
[[Category: Schwartz TU]]
[[Category: Helical stack]]
[[Category: Whittle JRR]]
[[Category: Membrane]]
[[Category: Mrna transport]]
[[Category: Nuclear pore complex]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protein transport]]
[[Category: Translocation]]
[[Category: Transmembrane]]
[[Category: Transport]]
Retrieved from "https://proteopedia.org/3i5q"