2rm0: Difference between revisions

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==FBP28WW2 domain in complex with a PPPLIPPPP peptide==
==FBP28WW2 domain in complex with a PPPLIPPPP peptide==
<StructureSection load='2rm0' size='340' side='right' caption='[[2rm0]], [[NMR_Ensembles_of_Models | 8 NMR models]]' scene=''>
<StructureSection load='2rm0' size='340' side='right'caption='[[2rm0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rm0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RM0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rm0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RM0 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jup|2jup]], [[2rly|2rly]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rm0 OCA], [https://pdbe.org/2rm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rm0 RCSB], [https://www.ebi.ac.uk/pdbsum/2rm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rm0 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tcerg1, Taf2s ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rm0 OCA], [http://pdbe.org/2rm0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rm0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rm0 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TCRG1_MOUSE TCRG1_MOUSE]] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity). [[http://www.uniprot.org/uniprot/FMN1_MOUSE FMN1_MOUSE]] Plays a role in the formation of adherens junction and the polymerization of linear actin cables.<ref>PMID:15198975</ref> <ref>PMID:14647292</ref> 
[https://www.uniprot.org/uniprot/TCRG1_MOUSE TCRG1_MOUSE] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rm/2rm0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rm/2rm0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Macias, M J]]
[[Category: Mus musculus]]
[[Category: Martin-Malpartida, P]]
[[Category: Macias MJ]]
[[Category: Oschkinat, H]]
[[Category: Martin-Malpartida P]]
[[Category: Ramirez-Espain, X]]
[[Category: Oschkinat H]]
[[Category: Ruiz, L]]
[[Category: Ramirez-Espain X]]
[[Category: Actin-binding]]
[[Category: Ruiz L]]
[[Category: Cell junction]]
[[Category: Fbp28ww2]]
[[Category: Membrane]]
[[Category: Nucleus]]
[[Category: Phosphorylation]]
[[Category: Ppplipppp ligand]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
Retrieved from "https://proteopedia.org/2rm0"