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==Crystal structure of protein SCO4506 from Streptomyces coelicolor, Pfam DUF178==
==Crystal structure of protein SCO4506 from Streptomyces coelicolor, Pfam DUF178==
<StructureSection load='2nxo' size='340' side='right' caption='[[2nxo]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='2nxo' size='340' side='right'caption='[[2nxo]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nxo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_coelicolor"_(muller_1908)_lieske_1921 "actinomyces coelicolor" (muller 1908) lieske 1921]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NXO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nxo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NXO FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Q9L0T8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1902 "Actinomyces coelicolor" (Muller 1908) Lieske 1921])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxo OCA], [http://pdbe.org/2nxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nxo RCSB], [http://www.ebi.ac.uk/pdbsum/2nxo PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2nxo TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxo OCA], [https://pdbe.org/2nxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nxo RCSB], [https://www.ebi.ac.uk/pdbsum/2nxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nxo ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2nxo TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MQNA_STRCO MQNA_STRCO]] Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).[HAMAP-Rule:MF_00995]  
[https://www.uniprot.org/uniprot/MQNA_STRCO MQNA_STRCO] Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).[HAMAP-Rule:MF_00995]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxo_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxo_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Burley, S K]]
[[Category: Large Structures]]
[[Category: Eswaramoorthy, S]]
[[Category: Streptomyces coelicolor]]
[[Category: Structural genomic]]
[[Category: Burley SK]]
[[Category: Swaminathan, S]]
[[Category: Eswaramoorthy S]]
[[Category: Tyagi, R]]
[[Category: Swaminathan S]]
[[Category: Duf178]]
[[Category: Tyagi R]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Pfam]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]