1uv6: Difference between revisions

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==X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH CARBAMYLCHOLINE==
 
<StructureSection load='1uv6' size='340' side='right' caption='[[1uv6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
==X-ray structure of acetylcholine binding protein (AChBP) in complex with carbamylcholine==
<StructureSection load='1uv6' size='340' side='right'caption='[[1uv6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uv6]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Great_pond_snail Great pond snail]. The November 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Acetylcholine Receptor''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_11 10.2210/rcsb_pdb/mom_2005_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UV6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uv6]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. The November 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Acetylcholine Receptor''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_11 10.2210/rcsb_pdb/mom_2005_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UV6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCE:2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM'>CCE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1i9b|1i9b]], [[1uw6|1uw6]], [[1ux2|1ux2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CCE:2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM'>CCE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uv6 OCA], [http://pdbe.org/1uv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uv6 RCSB], [http://www.ebi.ac.uk/pdbsum/1uv6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uv6 OCA], [https://pdbe.org/1uv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uv6 RCSB], [https://www.ebi.ac.uk/pdbsum/1uv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uv6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.  
[https://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST] Binds to acetylcholine. Modulates neuronal synaptic transmission.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uv/1uv6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uv/1uv6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Acetylcholine binding protein|Acetylcholine binding protein]]
*[[Acetylcholine binding protein 3D structures|Acetylcholine binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Acetylcholine Receptor]]
[[Category: Acetylcholine Receptor]]
[[Category: Great pond snail]]
[[Category: Large Structures]]
[[Category: Lymnaea stagnalis]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Brejc, K]]
[[Category: Brejc K]]
[[Category: Celie, P H.N]]
[[Category: Celie PHN]]
[[Category: Dijk, W J.Van]]
[[Category: Sixma TK]]
[[Category: Rossum-Fikkert, S E.Van]]
[[Category: Smit AB]]
[[Category: Sixma, T K]]
[[Category: Van Dijk WJ]]
[[Category: Smit, A B]]
[[Category: Van Rossum-fikkert SE]]
[[Category: Glycoprotein]]
[[Category: Igg fold]]
[[Category: Immunoglobulin domain]]
[[Category: Pentamer]]
Retrieved from "https://proteopedia.org/1uv6"