2ix3: Difference between revisions

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==STRUCTURE OF YEAST ELONGATION FACTOR 3==
 
<StructureSection load='2ix3' size='340' side='right' caption='[[2ix3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
==Structure of yeast Elongation Factor 3==
<StructureSection load='2ix3' size='340' side='right'caption='[[2ix3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ix3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IX3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ix3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IX3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iw3|2iw3]], [[2iwh|2iwh]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ix3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix3 OCA], [http://pdbe.org/2ix3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ix3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ix3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ix3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix3 OCA], [https://pdbe.org/2ix3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ix3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ix3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EF3A_YEAST EF3A_YEAST] Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis. Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied.<ref>PMID:6456269</ref> <ref>PMID:7657623</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ix3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ix3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Elongation factor|Elongation factor]]
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Anand, M]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Andersen, C B.F]]
[[Category: Anand M]]
[[Category: Andersen, G R]]
[[Category: Andersen CBF]]
[[Category: Balar, B]]
[[Category: Andersen GR]]
[[Category: Becker, T]]
[[Category: Balar B]]
[[Category: Beckmann, R]]
[[Category: Becker T]]
[[Category: Blau, M]]
[[Category: Beckmann R]]
[[Category: Boesen, T]]
[[Category: Blau M]]
[[Category: Halic, M]]
[[Category: Boesen T]]
[[Category: Kinzy, T G]]
[[Category: Halic M]]
[[Category: Mielke, T]]
[[Category: Kinzy TG]]
[[Category: Pedersen, J S]]
[[Category: Mielke T]]
[[Category: Spahn, C M.T]]
[[Category: Pedersen JS]]
[[Category: Atp-binding]]
[[Category: Spahn CMT]]
[[Category: Elongation factor]]
[[Category: Nucleotide-binding]]
[[Category: Phosphorylation]]
[[Category: Protein biosynthesis]]
[[Category: Rna-binding]]
[[Category: Rrna-binding]]
[[Category: Translation]]
Retrieved from "https://proteopedia.org/2ix3"