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==Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor==
==Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor==
<StructureSection load='3fiw' size='340' side='right' caption='[[3fiw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3fiw' size='340' side='right'caption='[[3fiw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fiw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_coelicolor"_(muller_1908)_lieske_1921 "actinomyces coelicolor" (muller 1908) lieske 1921]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FIW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fiw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FIW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCJ9A.32, SCO0253 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1902 "Actinomyces coelicolor" (Muller 1908) Lieske 1921])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fiw OCA], [https://pdbe.org/3fiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fiw RCSB], [https://www.ebi.ac.uk/pdbsum/3fiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fiw ProSAT], [https://www.topsan.org/Proteins/MCSG/3fiw TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fiw OCA], [http://pdbe.org/3fiw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fiw RCSB], [http://www.ebi.ac.uk/pdbsum/3fiw PDBsum], [http://www.topsan.org/Proteins/MCSG/3fiw TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9S1N8_STRCO Q9S1N8_STRCO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/3fiw_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/3fiw_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chang, C]]
[[Category: Large Structures]]
[[Category: Edwards, A M]]
[[Category: Streptomyces coelicolor]]
[[Category: Gu, J]]
[[Category: Chang C]]
[[Category: Joachimiak, A]]
[[Category: Edwards AM]]
[[Category: Structural genomic]]
[[Category: Gu J]]
[[Category: Savchenko, A]]
[[Category: Joachimiak A]]
[[Category: Singer, A U]]
[[Category: Savchenko A]]
[[Category: Xu, X]]
[[Category: Singer AU]]
[[Category: Dna-binding]]
[[Category: Xu X]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tetr-family transcriptional regulator streptomyce]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]

Latest revision as of 01:48, 21 November 2024

Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor

3fiw, resolution 2.20Å

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