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==The Crystal Structure of the Tudor Domains from FXR1==
==The Crystal Structure of the Tudor Domains from FXR1==
<StructureSection load='3kuf' size='340' side='right' caption='[[3kuf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3kuf' size='340' side='right'caption='[[3kuf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3kuf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KUF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KUF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3kuf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KUF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h8z|3h8z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FXR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kuf OCA], [https://pdbe.org/3kuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kuf RCSB], [https://www.ebi.ac.uk/pdbsum/3kuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kuf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kuf OCA], [http://pdbe.org/3kuf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kuf RCSB], [http://www.ebi.ac.uk/pdbsum/3kuf PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FXR1_HUMAN FXR1_HUMAN]] RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity).  
[https://www.uniprot.org/uniprot/FXR1_HUMAN FXR1_HUMAN] RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/3kuf_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/3kuf_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Adams-Cioaba, M A]]
[[Category: Large Structures]]
[[Category: Arrowsmith,C H]]
[[Category: Adams-Cioaba MA]]
[[Category: Bian,C]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev,A]]
[[Category: Bian C]]
[[Category: Bountra, C]]
[[Category: Bochkarev A]]
[[Category: Edwards,A M]]
[[Category: Bountra C]]
[[Category: Guo, Y H]]
[[Category: Edwards AM]]
[[Category: Kozieradzki, I]]
[[Category: Guo YH]]
[[Category: Mackenzie, F]]
[[Category: Kozieradzki I]]
[[Category: Min,J]]
[[Category: Mackenzie F]]
[[Category: Structural genomic]]
[[Category: Min J]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: Protein binding]]
[[Category: Rna-binding fragile x mental retardation syndrome-related protein 1]]
[[Category: Sgc]]
[[Category: Tandem tudor]]

Latest revision as of 08:23, 6 September 2023

The Crystal Structure of the Tudor Domains from FXR1

3kuf, resolution 2.70Å

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