2eg9: Difference between revisions
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==Crystal structure of the truncated extracellular domain of mouse CD38== | ==Crystal structure of the truncated extracellular domain of mouse CD38== | ||
<StructureSection load='2eg9' size='340' side='right' caption='[[2eg9]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='2eg9' size='340' side='right'caption='[[2eg9]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2eg9]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2eg9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EG9 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eg9 OCA], [https://pdbe.org/2eg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eg9 RCSB], [https://www.ebi.ac.uk/pdbsum/2eg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eg9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eg9 TOPSAN]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CD38_MOUSE CD38_MOUSE] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2eg9_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2eg9_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Hara-Yokoyama | [[Category: Mus musculus]] | ||
[[Category: Kukimoto-Niino | [[Category: Hara-Yokoyama M]] | ||
[[Category: Mishima | [[Category: Kukimoto-Niino M]] | ||
[[Category: Mishima C]] | |||
[[Category: Shirouzu | [[Category: Shirouzu M]] | ||
[[Category: Terada | [[Category: Terada T]] | ||
[[Category: Wakiyama | [[Category: Wakiyama M]] | ||
[[Category: Yokoyama | [[Category: Yokoyama S]] | ||
Latest revision as of 05:11, 17 October 2024
Crystal structure of the truncated extracellular domain of mouse CD38
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