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==Crystal structure of organophosphorus hydrolase from Geobacillus stearothermophilus strain 10, with glycerol bound==
==Crystal structure of organophosphorus hydrolase from Geobacillus stearothermophilus strain 10, with glycerol bound==
<StructureSection load='3f4c' size='340' side='right' caption='[[3f4c]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='3f4c' size='340' side='right'caption='[[3f4c]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3f4c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_stearothermophilus_10 Bacillus stearothermophilus 10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F4C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3f4c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus_10 Geobacillus stearothermophilus 10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F4C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f4d|3f4d]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f4c OCA], [https://pdbe.org/3f4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f4c RCSB], [https://www.ebi.ac.uk/pdbsum/3f4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f4c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f4c OCA], [http://pdbe.org/3f4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f4c RCSB], [http://www.ebi.ac.uk/pdbsum/3f4c PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D0VX06_GEOS3 D0VX06_GEOS3]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f4/3f4c_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f4/3f4c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus stearothermophilus 10]]
[[Category: Geobacillus stearothermophilus 10]]
[[Category: Aikens, J]]
[[Category: Large Structures]]
[[Category: Hawwa, R]]
[[Category: Aikens J]]
[[Category: Mesecar, A]]
[[Category: Hawwa R]]
[[Category: Santarsiero, B]]
[[Category: Mesecar A]]
[[Category: Turner, R J]]
[[Category: Santarsiero B]]
[[Category: Alpha-beta barrel]]
[[Category: Turner RJ]]
[[Category: Amidohydrolase]]
[[Category: Binuclear metal enzyme]]
[[Category: Glycerol-bound]]
[[Category: Hydrolase]]

Latest revision as of 06:41, 6 September 2023

Crystal structure of organophosphorus hydrolase from Geobacillus stearothermophilus strain 10, with glycerol bound

3f4c, resolution 2.07Å

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