3dyr: Difference between revisions

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==Crystal structure of E. coli thioredoxin mutant I76T in its oxidized form==
==Crystal structure of E. coli thioredoxin mutant I76T in its oxidized form==
<StructureSection load='3dyr' size='340' side='right' caption='[[3dyr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3dyr' size='340' side='right'caption='[[3dyr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dyr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DYR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DYR FirstGlance]. <br>
<table><tr><td colspan='2'>[[3dyr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DYR FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trxA, fipA, tsnC, b3781, JW5856 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dyr OCA], [http://pdbe.org/3dyr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dyr RCSB], [http://www.ebi.ac.uk/pdbsum/3dyr PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dyr OCA], [https://pdbe.org/3dyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dyr RCSB], [https://www.ebi.ac.uk/pdbsum/3dyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dyr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.  
[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/3dyr_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/3dyr_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Thioredoxin|Thioredoxin]]
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Bardwell, J C.A]]
[[Category: Large Structures]]
[[Category: Ren, G]]
[[Category: Bardwell JCA]]
[[Category: Xu, Z]]
[[Category: Ren G]]
[[Category: Electron transport]]
[[Category: Xu Z]]
[[Category: Host-virus interaction]]
[[Category: Mutant protein]]
[[Category: Redox-active center]]
[[Category: Transport]]

Latest revision as of 07:56, 9 October 2024

Crystal structure of E. coli thioredoxin mutant I76T in its oxidized form

3dyr, resolution 2.00Å

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