2dh7: Difference between revisions

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==Solution structure of the second RNA binding domain in Nucleolysin TIAR==
==Solution structure of the second RNA binding domain in Nucleolysin TIAR==
<StructureSection load='2dh7' size='340' side='right' caption='[[2dh7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2dh7' size='340' side='right'caption='[[2dh7]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dh7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DH7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DH7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dh7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DH7 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TIAL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dh7 OCA], [http://pdbe.org/2dh7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dh7 RCSB], [http://www.ebi.ac.uk/pdbsum/2dh7 PDBsum], [http://www.topsan.org/Proteins/RSGI/2dh7 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dh7 OCA], [https://pdbe.org/2dh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dh7 RCSB], [https://www.ebi.ac.uk/pdbsum/2dh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dh7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dh7 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TIAR_HUMAN TIAR_HUMAN]] RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.  
[https://www.uniprot.org/uniprot/TIAR_HUMAN TIAR_HUMAN] RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/2dh7_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/2dh7_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Imai, T]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Imai T]]
[[Category: Kigawa, T]]
[[Category: Inoue M]]
[[Category: Muto, Y]]
[[Category: Kigawa T]]
[[Category: Structural genomic]]
[[Category: Muto Y]]
[[Category: Shirouzu, M]]
[[Category: Shirouzu M]]
[[Category: Terada, T]]
[[Category: Terada T]]
[[Category: Tsuda, K]]
[[Category: Tsuda K]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rna binding protein]]
[[Category: Rrm domain]]
[[Category: Rsgi]]
Retrieved from "https://proteopedia.org/2dh7"