5hsi: Difference between revisions
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==Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution== | |||
<StructureSection load='5hsi' size='340' side='right'caption='[[5hsi]], [[Resolution|resolution]] 1.73Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5hsi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis Levilactobacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HSI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.732Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
[[Category: Ni | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hsi OCA], [https://pdbe.org/5hsi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hsi RCSB], [https://www.ebi.ac.uk/pdbsum/5hsi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hsi ProSAT]</span></td></tr> | ||
[[Category: Zhang | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/TYRDC_LEVBR TYRDC_LEVBR] Catalyzes the decarboxylation of L-tyrosine to produce tyramine (PubMed:24211777, PubMed:27292129). Cannot use other aromatic L-amino acids as substrates like L-phenylalanine, L-tryptophan and L-glutamate (PubMed:24211777).<ref>PMID:24211777</ref> <ref>PMID:27292129</ref> Is also able to decarboxylate the Parkinson's disease medication levodopa (L-dopa) to dopamine in vitro.<ref>PMID:24211777</ref> <ref>PMID:27292129</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Levilactobacillus brevis]] | |||
[[Category: Ni Y]] | |||
[[Category: Zhang K]] | |||
[[Category: Zhou J]] | |||
[[Category: Zhu H]] | |||
Latest revision as of 09:15, 20 March 2024
Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution
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