PcrH: Difference between revisions

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<StructureSection load='2xcb' size='340' side='right' caption='PcrH (grey, green) complex with PopD chaperone binding peptide (pink) and NO3- ion (PDB code [[2xcb]])' scene=''>
<StructureSection load='' size='350' side='right' caption='PcrH (magenta, green) complex with PopD chaperone binding peptide (cyan) and NO3- ion (PDB code [[2xcb]])' scene='72/725368/Cv/1'>


== Function ==
== Function ==


'''PcrH''' or Regulatory protein PcrH is a chaperone protein which is a member of the translocon system which enables bacteria to form a pore in the cell wall for the insertion of toxins into it.  See details in [[Molecular Playground/Pcr H]].
'''PcrH''' or Regulatory protein PcrH is a chaperone protein which is a member of the translocon system which enables bacteria to form a pore in the cell wall for the insertion of toxins into it<ref>PMID:14673772</ref>.  See details in [[Molecular Playground/Pcr H]].


== Structural highlights ==
== Structural highlights ==


PcrH contains a helical Tpr domain (tetratricopeptide) which interacts with the translocator PopD or PopB peptide<ref>PMID:20385547</ref>. PopD peptide binds at the concave surface of PcrH.
<scene name='72/725368/Cv/6'>PcrH contains a helical Tpr domain (tetratricopeptide) which interacts with the translocator PopD</scene> or PopB peptide. Water molecules are shown as red spheres. PopD peptide binds at the concave surface of PcrH. <scene name='72/725368/Cv/7'>NO3- ion binding site</scene> (PDB code [[2xcb]]). <ref>PMID:20385547</ref>


</StructureSection>
</StructureSection>
== 3D Structures of lactoferrin ==
== 3D Structures of PcrH ==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]

Latest revision as of 12:36, 29 July 2019

PcrH (magenta, green) complex with PopD chaperone binding peptide (cyan) and NO3- ion (PDB code 2xcb)

Drag the structure with the mouse to rotate

3D Structures of PcrH

Updated on 29-July-2019

Molecular Playground/Pcr H - PaPcrH – Pseudomonas aeruginosa
2xcb - PaPcrH + PopD chaperone-binding peptide
4jl0 - PaPcrH + PopB chaperone-binding peptide

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman