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==Crystal Structure of chromodomain of CBX8 in complex with inhibitor UNC3866==
==Crystal Structure of chromodomain of CBX8 in complex with inhibitor UNC3866==
<StructureSection load='5eq0' size='340' side='right' caption='[[5eq0]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
<StructureSection load='5eq0' size='340' side='right'caption='[[5eq0]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5eq0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EQ0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5eq0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQ0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.18&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5R0:4-~{TERT}-BUTYLBENZOIC+ACID'>5R0</scene>, <scene name='pdbligand=5R5:METHYL+(2~{S})-2-AZANYL-3-OXIDANYL-PROPANOATE'>5R5</scene>, <scene name='pdbligand=ELY:N~6~,N~6~-DIETHYL-L-LYSINE'>ELY</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5R0:4-~{TERT}-BUTYLBENZOIC+ACID'>5R0</scene>, <scene name='pdbligand=5R5:METHYL+(2~{S})-2-AZANYL-3-OXIDANYL-PROPANOATE'>5R5</scene>, <scene name='pdbligand=ELY:N~6~,N~6~-DIETHYL-L-LYSINE'>ELY</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ebj|5ebj]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eq0 OCA], [https://pdbe.org/5eq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eq0 RCSB], [https://www.ebi.ac.uk/pdbsum/5eq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eq0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eq0 OCA], [http://pdbe.org/5eq0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eq0 RCSB], [http://www.ebi.ac.uk/pdbsum/5eq0 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBX8_HUMAN CBX8_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Dickson, B M]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M]]
[[Category: Bountra C]]
[[Category: Frye, S V]]
[[Category: Dickson BM]]
[[Category: James, L I]]
[[Category: Edwards AM]]
[[Category: Liu, Y]]
[[Category: Frye SV]]
[[Category: Min, J]]
[[Category: James LI]]
[[Category: Structural genomic]]
[[Category: Liu Y]]
[[Category: Stuckey, J I]]
[[Category: Min J]]
[[Category: Tempel, W]]
[[Category: Stuckey JI]]
[[Category: Walker, J R]]
[[Category: Tempel W]]
[[Category: Sgc]]
[[Category: Walker JR]]
[[Category: Transcription-transcription inhibitor complex]]
Retrieved from "https://proteopedia.org/5eq0"