5i3o: Difference between revisions
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New page: '''Unreleased structure''' The entry 5i3o is ON HOLD Authors: Counago, R.M., Sorrell, F.J., Krojer, T., Elkins, J.M., Gileadi, O., Willson, T.M., Arrowsmith, C.H., Edwards, A.M., Bountr... |
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==Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor== | |||
<StructureSection load='5i3o' size='340' side='right'caption='[[5i3o]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5i3o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I3O FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IDV:N-(6-{3-[(DIMETHYLSULFAMOYL)AMINO]PHENYL}-1H-INDAZOL-3-YL)CYCLOPROPANECARBOXAMIDE'>IDV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i3o OCA], [https://pdbe.org/5i3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i3o RCSB], [https://www.ebi.ac.uk/pdbsum/5i3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i3o ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Bountra | [https://www.uniprot.org/uniprot/BMP2K_HUMAN BMP2K_HUMAN] May be involved in osteoblast differentiation. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Edwards | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Gileadi | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Arruda P]] | ||
[[Category: | [[Category: Axtman A]] | ||
[[Category: Bountra C]] | |||
[[Category: Counago RM]] | |||
[[Category: Drewry D]] | |||
[[Category: Edwards AM]] | |||
[[Category: Elkins JM]] | |||
[[Category: Gileadi O]] | |||
[[Category: Krojer T]] | |||
[[Category: Savitsky P]] | |||
[[Category: Sorrell FJ]] | |||
[[Category: Wells C]] | |||
[[Category: Willson TM]] | |||
[[Category: Zhang C]] | |||
[[Category: Zuercher W]] | |||
Latest revision as of 08:22, 23 August 2023
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
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