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'''Unreleased structure'''


The entry 2nbh is ON HOLD
==Solution structure of the HYD1 hydrophobin from Schizophyllum commune==
<StructureSection load='2nbh' size='340' side='right'caption='[[2nbh]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2nbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizophyllum_commune_H4-8 Schizophyllum commune H4-8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NBH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nbh OCA], [https://pdbe.org/2nbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nbh RCSB], [https://www.ebi.ac.uk/pdbsum/2nbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nbh ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Class I hydrophobins are functional amyloids secreted by fungi. They self-assemble into organized films at interfaces producing structures that include cellular adhesion points and hydrophobic coatings. Here, we present the first structure and solution properties of a unique Class I protein sequence of Basidiomycota origin: the Schizophyllum commune hydrophobin SC16 (hyd1). While the core beta-barrel structure and disulphide bridging characteristic of the hydrophobin family are conserved, its surface properties and secondary structure elements are reminiscent of both Class I and II hydrophobins. Sequence analyses of hydrophobins from 215 fungal species suggest this structure is largely applicable to a high-identity Basidiomycota Class I subdivision (IB). To validate this prediction, structural analysis of a comparatively distinct Class IB sequence from a different fungal order, namely the Phanerochaete carnosa PcaHyd1, indicates secondary structure properties similar to that of SC16. Together, these results form an experimental basis for a high-identity Class I subdivision and contribute to our understanding of functional amyloid formation.


Authors: Langelaan, D., Smith, S., Grondin, J.
Characterization of a Basidiomycota hydrophobin reveals the structural basis for a high-similarity Class I subdivision.,Gandier JA, Langelaan DN, Won A, O'Donnell K, Grondin JL, Spencer HL, Wong P, Tillier E, Yip C, Smith SP, Master ER Sci Rep. 2017 Apr 10;7:45863. doi: 10.1038/srep45863. PMID:28393921<ref>PMID:28393921</ref>


Description: Solution structure of the HYD1 hydrophobin from Schizophyllum commune
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Langelaan, D]]
<div class="pdbe-citations 2nbh" style="background-color:#fffaf0;"></div>
[[Category: Grondin, J]]
== References ==
[[Category: Smith, S]]
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizophyllum commune H4-8]]
[[Category: Grondin J]]
[[Category: Langelaan D]]
[[Category: Smith S]]
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