5ign: Difference between revisions

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New page: '''Unreleased structure''' The entry 5ign is ON HOLD Authors: Tallant, C., Clark, P.G.K., Vieira, L.C.C., Newman, J.A., Krojer, T., Nunez-Alonso, G., Picaud, S., Fedorov, O., Dixon, D.J...
 
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'''Unreleased structure'''


The entry 5ign is ON HOLD
==Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe==
<StructureSection load='5ign' size='340' side='right'caption='[[5ign]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ign]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IGN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ign FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ign OCA], [https://pdbe.org/5ign PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ign RCSB], [https://www.ebi.ac.uk/pdbsum/5ign PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ign ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription.


Authors: Tallant, C., Clark, P.G.K., Vieira, L.C.C., Newman, J.A., Krojer, T., Nunez-Alonso, G., Picaud, S., Fedorov, O., Dixon, D.J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Brennan, P.E., Knapp, S., Structural Genomics Consortium (SGC)
==See Also==
 
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
Description: Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Nunez-Alonso, G]]
[[Category: Homo sapiens]]
[[Category: Fedorov, O]]
[[Category: Large Structures]]
[[Category: Vieira, L.C.C]]
[[Category: Arrowsmith CH]]
[[Category: Picaud, S]]
[[Category: Bountra C]]
[[Category: Knapp, S]]
[[Category: Brennan PE]]
[[Category: Clark, P.G.K]]
[[Category: Clark PGK]]
[[Category: Krojer, T]]
[[Category: Dixon DJ]]
[[Category: Bountra, C]]
[[Category: Edwards AM]]
[[Category: Arrowsmith, C.H]]
[[Category: Fedorov O]]
[[Category: Von Delft, F]]
[[Category: Knapp S]]
[[Category: Edwards, A.M]]
[[Category: Krojer T]]
[[Category: Dixon, D.J]]
[[Category: Newman JA]]
[[Category: Brennan, P.E]]
[[Category: Nunez-Alonso G]]
[[Category: Newman, J.A]]
[[Category: Picaud S]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Tallant C]]
[[Category: Tallant, C]]
[[Category: Vieira LCC]]
[[Category: Von Delft F]]

Latest revision as of 13:51, 30 August 2023

Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe

5ign, resolution 1.70Å

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