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==Crystal structure of the bromodomain of BRD9 in complex with compound 9.==
==Crystal structure of the bromodomain of BRD9 in complex with compound 9.==
<StructureSection load='5f1l' size='340' side='right' caption='[[5f1l]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5f1l' size='340' side='right'caption='[[5f1l]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5f1l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F1L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F1L FirstGlance]. <br>
<table><tr><td colspan='2'>[[5f1l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F1L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5U2:5-[3,5-DIMETHOXY-4-[(3-OXIDANYLAZETIDIN-1-YL)METHYL]PHENYL]-1,3-DIMETHYL-PYRIDIN-2-ONE'>5U2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f1h|5f1h]], [[5eu1|5eu1]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5U2:5-[3,5-DIMETHOXY-4-[(3-OXIDANYLAZETIDIN-1-YL)METHYL]PHENYL]-1,3-DIMETHYL-PYRIDIN-2-ONE'>5U2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f1l OCA], [http://pdbe.org/5f1l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f1l RCSB], [http://www.ebi.ac.uk/pdbsum/5f1l PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f1l OCA], [https://pdbe.org/5f1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f1l RCSB], [https://www.ebi.ac.uk/pdbsum/5f1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f1l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN]] May play a role in chromatin remodeling and regulation of transcription.  
[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5f1l" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5f1l" style="background-color:#fffaf0;"></div>
==See Also==
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bader, G]]
[[Category: Homo sapiens]]
[[Category: Martin, L J]]
[[Category: Large Structures]]
[[Category: Steurer, S]]
[[Category: Bader G]]
[[Category: Weiss-Puxbaum, A]]
[[Category: Martin LJ]]
[[Category: Zoephel, A]]
[[Category: Steurer S]]
[[Category: Bromodomain]]
[[Category: Weiss-Puxbaum A]]
[[Category: Inhibitor]]
[[Category: Zoephel A]]
[[Category: Transcription]]

Latest revision as of 08:40, 12 July 2023

Crystal structure of the bromodomain of BRD9 in complex with compound 9.

5f1l, resolution 2.30Å

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